NT PRO PÉPTIDO NATRIURÉTICO CEREBRAL VERSUS APACHE II COMO PREDICTOR DE MORTALIDAD EN SHOCK SÉPTICO

Abstract

Brain natriuretic peptide (PNA) is a peptide hormone, and N-terminal pro-B-type natriuretic peptide (NT-proBNP) which is determined to be a stress marker of the ventricular wall and is released by the muscle cells of the cardiac atrium as a natural response to increased blood pressure. Septic shock is a consequence of a generalized infection of the organism, caused by a pathogen or microorganism to which the organism responds with an inflammation because of the generalized tissue damage in the organism. Elevated levels of PNA are associated with increased mortality in patients diagnosed with septic shock, and measurements of this hormone can be compared with the results obtained from the APACHE II score in order to analyze which method is more reliable. The study is a prospective and descriptive study applied to patients admitted to the Intensive Care Unit of the Luis Vernaza Hospital by analyzing the elevated values of NT-proBNP relative to the APACHE II score to determine which method is more reliable as a predictor of Mortality in patients diagnosed with septic shock, the total number of study subjects was 58 patients, mainly women with an incidence of 58.6% and a mortality rate of 52.9%. Of the total number of patients studied, the most frequent complication was hypertension for both living and Deceased It was determined that patients with higher ANP had a higher mortality in relation to APACHE II mainly in levels between 20-24. Determining that NT-proBNP along with APACHE II function as a reliable indicator of mortality.