CLASIFICACIÓN MOLECULAR DE CÁNCER DE MAMA EN PACIENTES FEMENINOS. HOSPITAL TEODORO MALDONADO CARBO. ENERO-JUNIO 2016.

Abstract

Introduction: Breast cancer is the most common cancer in women in the world. During the last 15 years, treatments have been personalized due to the molecular classification of the disease. Objective: To describe the molecular classification of breast cancer in female patients. Methodology: Descriptive, retrospective study of qualitative approach, carried out in the Hospital Teodoro Maldonado Carbo; in patients over 18 years of age, female gender diagnosed with breast cancer in the 2016 period. A sample of 111 patients who met the inclusion criteria was obtained. They were stored in Microsoft Excel, they were processed through the statistical program SPSS through frequency and relationship measurements. Results: Luminal A molecular class predominated with 37.9%, followed by the class Triple negative (23.4%) and class Luminal B and Su 2+ with the similar frequency. The most frequent group was 61 to 70 years (27.9%), followed by 51 to 60 years (26.1%). Ductal adenocarcinoma was the most frequent histological type with 98.2%. 21.9% of the population is in stage II that indicates a cancer spread to axillary lymph nodes; tumor measures less than 20 mm; or lesion smaller than 50 mm and that has not taken axillary ganglia. Finally, there is no relationship between molecular classification and clinical stage. Conclusion: The molecular class of breast cancer most frequent in the study participants is Luminal A, whose prognosis is favorable in comparison to the other subtypes according to the literature.