HIPOALBUMINEMIA COMO FACTOR PREDICTIVO DE MORTALIDAD EN SEPSIS NEONATAL EN LA UCIN DEL HOSPITAL DR. ROBERTO GILBERT DE GUAYAQUIL, AÑO 2016

Abstract

Neonatal sepsis is a syndrome of systemic inflammatory response to the presence of a suspected or proven infection. According to its presentation time it is divided into early-onset or late-onset sepsis and has numerous etiologies as well as risk factors. Hypoalbuminemia is the condition of serum albumin levels lower than 2.5 g / dl in infants under 7 months of age. The objective of this observational retrospective analytical study was to determine the relationship between hypoalbuminemia and mortality in neonates with sepsis in the NICU of the Dr. Roberto Gilbert Hospital in Guayaquil, 2016. In addition to determining the frequency of mortality in neonates with sepsis and the frequency of hypoalbuminemia in neonates deceased due to sepsis. 295 newborn patients who met the inclusion criteria of the study were analyzed. 167 were male and 128 were female. 234 had episodes of early-onset sepsis while 61 had late-onset sepsis. The total mortality was 31.9%. 20.3% of the total patients had hypoalbuminemia. Of the patients who died, 47.9% showed low serum albumin values. It was concluded that hypoalbuminemia is a predictive factor of mortality when the hypothesis is tested as positive. Hypoalbuminemia (p <0.001, OR═11.39 IC═95%) is a statistically significant variable for the prediction of mortality in neonatal sepsis. Key words: neonatal sepsis, NICU, hypoalbuminemia, mortality