CARACTERIZACIÓN CLÍNICO-EPIDEMIOLÓGICA DE NEUROCRIPTOCOCOSIS EN PACIENTES CON VIH/SIDA EN EL HOSPITAL DE INFECTOLOGÍA “DR. JOSÉ DANIEL RODRÍGUEZ MARIDUEÑA”, 2016

Abstract

Background: Cryptococcal meningitis is one of the most frequent opportunistic infections HIV-positive individuals, constituting a disease defining AIDS. Objective: Clinically and epidemiologically characterize neurocriptococcosis in patients with HIV-AIDS from the hospital of Infectología "Dr. José Daniel Rodríguez Maridueña" Methodology: 120 HIV-positive patients with neurological syndrome who attended the Hospital de Infectología during 2016 were studied. Clinicalepidemiological data were obtained through a clinical record, in addition to the results reported by the hospital laboratory of microbiological culture and direct observation by Chinese ink. The data obtained were analyzed with the statistical software SPSS, applying measures of percentage, frequency and relation by Chi-square test. Results: The prevalence of Cryptococcus-HIV coinfection was 25.0%. It was clinically characterized by fever (86.7%), headache (83.3%), weight loss (83.3%) and vomiting (80.0%). Epidemiologically, the age group most affected was 31 to 40 years (43.3%), with male sex predominated (83.7%). Conclusions: The prevalence of neurocriptococcosis shows that it constitutes a health problem in patients with HIV-AIDS and neurological syndrome in Guayaquil.