“COCIENTE VOLUMEN PLAQUETARIO MEDIO /LINFOCÍTICO COMO FACTOR PREDICTIVO DE MORTALIDAD INTRAHOSPITALARIA EN PACIENTES CON INFARTO AGUDO DE MIOCARDIO EN HOSPITAL DE ESPECIALIDADES TEODORO MALDONADO CARBO, 2017”

Abstract

Introduction: Low-grade inflammation, endothelial dysfunction and platelet hyperreactivity are independently associated with an increased risk of cardiovascular events. It is suggested that mean / lymphocytic platelet volume (VPML) ratio is a marker of in-hospital mortality in patients with acute myocardial infarction. Methodology: A total of 94 patients were selected from January to December of the year 2017 with a diagnosis of acute myocardial infarction that presented a complete blood count within the first 48 hours. The cut-off point of the Mean / Lymphocytic Platelet Volume was 7.38 according to the distribution of the data, dividing the sample into two groups. Results: Despite similar clinical characteristics, patients with elevated LVMP had worse angiography. In-hospital mortality was higher in the high-VLML group. The ROC analysis revealed a moderate diagnostic value to predict in-hospital mortality (HR 1.112, 95% CI 1.003-1.234, P = 0.044, VPML cutoff = 7.38). Conclusion: It was determined that there is a statistically significant correlation between the mean / lymphocytic platelet volume ratio and mortality (p = 0.001).