Complicaciones infecciosas postrasplante autólogo de células madre hematopoyéticas en pacientes con mieloma múltiple

Abstract

Introduction: The survival rate of patients with multiple myeloma has increased due to autologous hematopoietic stem cell transplantation. However, these patients can develop serious infections after such treatment. Objective: To describe the most frequent infectious complications in patients with multiple myeloma after autologous hematopoietic stem cell transplantation. Methodology: A systematic review was carried out according to the PRISMA guideline in PubMed from 2013 to 2024. Results: Gram-negative and gram-positive bacterial infections are the most frequent in patients with multiple myeloma; certain factors can aggravate the clinical condition of patients, leading to the development of bacteremia and opportunistic infections. Conclusions: Timely and preventive management of infections is important to improve the quality of life of patients with multiple myeloma. Key words: multiple myeloma, infections, prevention, autologous transplant, hematopoietic stem cells.